Arabidopsis COP10 forms a complex with DDB1 and DET1 in vivo and enhances the activity of ubiquitin conjugating enzymes.

@article{Yanagawa2004ArabidopsisCF,
  title={Arabidopsis COP10 forms a complex with DDB1 and DET1 in vivo and enhances the activity of ubiquitin conjugating enzymes.},
  author={Yuki Yanagawa and James Andrew Sullivan and Setsuko Komatsu and Giuliana Gusmaroli and Genki Suzuki and Jian-ning Yin and Toyotaka Ishibashi and Yusuke Saijo and Vicente Rubio and Seisuke Kimura and Jian Wang and Xing Wang Deng},
  journal={Genes & development},
  year={2004},
  volume={18 17},
  pages={2172-81}
}
COP10 is a ubiquitin-conjugating enzyme variant (UEV), which is thought to act together with COP1, DET1, and the COP9 signalosome (CSN) in Arabidopsis to repress photomorphogenesis. Here, we demonstrate that COP10 interacts with ubiquitin-conjugating enzymes (E2s) in vivo, and can enhance their activity in vitro, an activity distinct from previous characterized UEVs such as MMS2 and UEV1. Furthermore, we show that COP10 forms a complex with UV-damaged DNA-binding protein 1a (DDB1a) and de… CONTINUE READING
Highly Influential
This paper has highly influenced 20 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 89 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 46 references

Similar Papers

Loading similar papers…