Arabidopsis C-terminal domain phosphatase-like 1 and 2 are essential Ser-5-specific C-terminal domain phosphatases.

@article{Koiwa2004ArabidopsisCD,
  title={Arabidopsis C-terminal domain phosphatase-like 1 and 2 are essential Ser-5-specific C-terminal domain phosphatases.},
  author={Hisashi Koiwa and St{\'e}phane Hausmann and Woo Young Bang and Akihiro Ueda and Naoko Iwahashi Kondo and Akihiro Hiraguri and Toshiyuki Fukuhara and Jeong Dong Bahk and Dae-Jin Yun and Ray Anthony Bressan and Paul Mike Hasegawa and Stewart Shuman},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2004},
  volume={101 40},
  pages={14539-44}
}
Transcription and mRNA processing are regulated by phosphorylation and dephosphorylation of the C-terminal domain (CTD) of RNA polymerase II, which consists of tandem repeats of a Y(1)S(2)P(3)T(4)S(5)P(6)S(7) heptapeptide. Previous studies showed that members of the plant CTD phosphatase-like (CPL) protein family differentially regulate osmotic stress-responsive and abscisic acid-responsive transcription in Arabidopsis thaliana. Here we report that AtCPL1 and AtCPL2 specifically dephosphorylate… CONTINUE READING