Ara6, a plant-unique novel type Rab GTPase, functions in the endocytic pathway of Arabidopsis thaliana.

@article{Ueda2001Ara6AP,
  title={Ara6, a plant-unique novel type Rab GTPase, functions in the endocytic pathway of Arabidopsis thaliana.},
  author={Takashi Ueda and Masa-atsu Yamaguchi and Hirofumi Uchimiya and Akihiko Nakano},
  journal={The EMBO journal},
  year={2001},
  volume={20 17},
  pages={4730-41}
}
Ara6 of Arabidopsis thaliana is a novel member of the Rab/Ypt GTPase family with unique structural features. It resembles Rab5 GTPases best, but lacks a large part of the C-terminal hypervariable region and the cysteine motif, and instead harbors an extra stretch of amino acid residues containing myristoylation and palmitoylation sites at the N-terminus. Ara6 is tightly associated with membranes and is expressed constitutively. In contrast, the conventional Rab5 ortholog, Ara7, is highly… CONTINUE READING