Aqueous ionic liquids and their influence on peptide conformations: denaturation and dehydration mechanisms.

@article{Diddens2017AqueousIL,
  title={Aqueous ionic liquids and their influence on peptide conformations: denaturation and dehydration mechanisms.},
  author={Diddo Diddens and Volker Lesch and Andreas Heuer and Jens Smiatek},
  journal={Physical chemistry chemical physics : PCCP},
  year={2017},
  volume={19 31},
  pages={20430-20440}
}
Low concentrated aqueous ionic liquids (ILs) and their influence on protein structures have attracted a lot of interest over the last few years. This can be mostly attributed to the fact that aqueous ILs, depending on the ion species involved, can be used as protein protectants or protein denaturants. Atomistic molecular dynamics (MD) simulations are performed in order to study the influence of different aprotic ILs on the properties of a short hairpin peptide. Our results reveal distinct… CONTINUE READING