Aqueous Sol-Gel Process for Protein Encapsulation

  title={Aqueous Sol-Gel Process for Protein Encapsulation},
  author={Rimple B. Bhatia and C Jeffrey Brinker and Alok Kr Gupta and Anup Singh},
Porous silica materials made by low-temperature sol-gel process are promising host matrixes for encapsulation of biomolecules. To date, researchers have focused on sol-gel routes using alkoxides such as tetramethyl orthosilicate (TMOS) and tetraethyl orthosilicate (TEOS) for encapsulation of biomolecules. These routes lead to formation of alcohol as a byproduct that can have a detrimental effect on the activity of entrapped biomolecules. We have developed a novel aqueous sol-gel process to… CONTINUE READING
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