Aquatic persistence of eight pharmaceuticals in a microcosm study

  title={Aquatic persistence of eight pharmaceuticals in a microcosm study},
  author={Monica W. Lam and Cora J. Young and Richard A. Brain and David J. Johnson and Mark A. Hanson and Christian J Wilson and Sean M Richards and Keith R. Solomon and Scott A. Mabury},
  journal={Environmental Toxicology and Chemistry},
The persistence of eight pharmaceuticals from multiple classes was studied in aquatic outdoor field microcosms. A method was developed for the determination of a mixture of acetaminophen, atorvastatin, caffeine, carbarnazepine, levofloxacin, sertraline, sulfamethoxazole, and trimethoprim at μg/L levels from surface water of the microcosms using solid phase extraction and high‐performance liquid chromatography‐ultraviolet (HPLC‐UV) and liquid chromatography tandem mass spectrometry (LC‐MS‐MS… 

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