Aquatic Acute Toxicity Testing Using the Nematode Caenorhabditis elegans

@inproceedings{Ura2002AquaticAT,
  title={Aquatic Acute Toxicity Testing Using the Nematode Caenorhabditis elegans},
  author={Kazuhiro Ura and Toshinori Kai and Sachiko Sakata and Taisen Iguchi and Koji Arizono},
  year={2002}
}
To evaluate the toxicity of environmental chemicals to invertebrates, a static bioassay was developed in the laboratory using the Caenorhabditis elegans (C. elegans). First, reproducibility of this aquatic acute toxicity test system was confirmed. In order to estimate chemical toxicities in C. elegans, worms were subsequently exposed to eleven different xenobiotics. Mortality after 24 hr was adopted as the endpoint of toxicity. We found that benzo[a]pyrene, nonylphenol, benzophenone, bisphenol… CONTINUE READING

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