Aquaporin expression correlates with freeze tolerance in baker's yeast, and overexpression improves freeze tolerance in industrial strains.

@article{Tanghe2002AquaporinEC,
  title={Aquaporin expression correlates with freeze tolerance in baker's yeast, and overexpression improves freeze tolerance in industrial strains.},
  author={An Tanghe and Patrick van Dijck and F. A. G. Dumortier and Aloys Teunissen and Stefan Hohmann and Johan M Thevelein},
  journal={Applied and environmental microbiology},
  year={2002},
  volume={68 12},
  pages={5981-9}
}
Little information is available about the precise mechanisms and determinants of freeze resistance in baker's yeast, Saccharomyces cerevisiae. Genomewide gene expression analysis and Northern analysis of different freeze-resistant and freeze-sensitive strains have now revealed a correlation between freeze resistance and the aquaporin genes AQY1 and AQY2. Deletion of these genes in a laboratory strain rendered yeast cells more sensitive to freezing, while overexpression of the respective genes… CONTINUE READING

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