Aquaporin changes during diabetic retinopathy in rats are accelerated by systemic hypertension and are linked to the renin-angiotensin system.

@article{Qin2012AquaporinCD,
  title={Aquaporin changes during diabetic retinopathy in rats are accelerated by systemic hypertension and are linked to the renin-angiotensin system.},
  author={Yaowu Qin and Hui Ren and Matthew R. Hoffman and Jiawen Fan and Meng Zhang and Gezhi Xu},
  journal={Investigative ophthalmology & visual science},
  year={2012},
  volume={53 6},
  pages={3047-53}
}
PURPOSE We explored the relationship between the renin-angiotensin system (RAS) and aquaporins (AQP1 and AQP4 in Müller glia and astrocytes) in diabetic retinopathy (DR) with and without systemic hypertension. METHODS Diabetes was induced in spontaneously hypertensive rats (SHR) and normotensive control Wistar Kyoto (WKY) rats by intraperitoneal… CONTINUE READING