Aquaporin 4: a player in cerebral edema and neuroinflammation

  title={Aquaporin 4: a player in cerebral edema and neuroinflammation},
  author={Andrew Fukuda and J{\'e}r{\^o}me Badaut},
  booktitle={Journal of Neuroinflammation},
Neuroinflammation is a common pathological event observed in many different brain diseases, frequently associated with blood brain barrier (BBB) dysfunction and followed by cerebral edema. Neuroinflammation is characterized with microglia activation and astrogliosis, which is a hypertrophy of the astrocytes. Astrocytes express aquaporin 4, the water channel protein, involved in water homeostasis and edema formation. Aside from its function in water homeostasis, recent studies started to show… CONTINUE READING


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