Aquaporin-2 expression in primary cultured rat inner medullary collecting duct cells.

@article{Maric1998Aquaporin2EI,
  title={Aquaporin-2 expression in primary cultured rat inner medullary collecting duct cells.},
  author={Kenan Maric and Alexander Oksche and Wesley Rosenthal},
  journal={The American journal of physiology},
  year={1998},
  volume={275 5 Pt 2},
  pages={F796-801}
}
Cultured renal epithelial cells rapidly downregulate expression of the vasopressin-regulated water channel aquaporin-2 (AQP-2). Our aim was to define conditions that favor maintenance of AQP-2 expression in vitro without genetic manipulation. We show here that primary cultures of rat inner medullary collecting duct (IMCD) cells retain AQP-2 expression for at least 6 days when grown with dibutyryl cAMP (DBcAMP) supplementation. We also found that coating the culture dishes with type IV collagen… CONTINUE READING
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Vasopressin and water transport in aquaporin-2 transfected mouse inner medullary collecting (IMCD) cell monolayers (Abstract)

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