Aquaporin-0 membrane junctions form upon proteolytic cleavage.

  title={Aquaporin-0 membrane junctions form upon proteolytic cleavage.},
  author={Tamir Gonen and Yifan Cheng and Joerg Kistler and Thomas Walz},
  journal={Journal of molecular biology},
  volume={342 4},
Aquaporin-0 (AQP0), previously known as major intrinsic protein (MIP), is the only water pore protein expressed in lens fiber cells. AQP0 is highly specific to lens fiber cells and constitutes the most abundant intrinsic membrane protein in these cells. The protein is initially expressed as a full-length protein in young fiber cells in the lens cortex, but becomes increasingly cleaved in the lens core region. Reconstitution of AQP0 isolated from the core of sheep lenses containing a proportion… CONTINUE READING
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