Aptamers: Active Targeting Ligands for Cancer Diagnosis and Therapy

  title={Aptamers: Active Targeting Ligands for Cancer Diagnosis and Therapy},
  author={Xu Wu and Jiao Chen and Min Wu and Julia Xiaojun Zhao},
Aptamers, including DNA, RNA and peptide aptamers, are a group of promising recognition units that can specifically bind to target molecules and cells. Due to their excellent specificity and high affinity to targets, aptamers have attracted great attention in various fields in which selective recognition units are required. They have been used in biosensing, drug delivery, disease diagnosis and therapy (especially for cancer treatment). In this review, we summarized recent applications of DNA… CONTINUE READING


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Aptamer - conjugated mn 3 o 4 @ sio 2 core - shell nanoprobes for targeted magnetic resonance imaging

  • H Hu, A Dai, J Sun, X Li, F Gao, L Wu
  • Nanoscale
  • 2013

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