Aptamer-labeled PLGA nanoparticles for targeting cancer cells

  title={Aptamer-labeled PLGA nanoparticles for targeting cancer cells},
  author={A. Aravind and S. H. Varghese and S. Veeranarayanan and A. Mathew and Y. Nagaoka and Seiki Iwai and T. Fukuda and Takashi Hasumura and Yasuhiko Yoshida and T. Maekawa and D. S. Kumar},
  journal={Cancer Nanotechnology},
  pages={1 - 12}
  • A. Aravind, S. H. Varghese, +8 authors D. S. Kumar
  • Published 2012
  • Materials Science, Medicine
  • Cancer Nanotechnology
  • Cancer is one of the leading causes of death in most parts of the world and is a very serious cause of concern particularly in developing countries. In this work, we prepared and evaluated the aptamer-labeled paclitaxel-loaded poly(lactic-co-glycolic acid) (PLGA) nanoparticles (Apt-PTX-PLGA NPs) which can ameliorate drug bioavailability and enable accurate drug targeting to cancer cells with controlled drug release for cancer therapy. Paclitaxel-loaded PLGA nanoparticles (PTX-PLGA NPs) were… CONTINUE READING
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