Aptamer-conjugated silver nanoparticles for electrochemical dual-aptamer-based sandwich detection of staphylococcus aureus.

@article{Abbaspour2015AptamerconjugatedSN,
  title={Aptamer-conjugated silver nanoparticles for electrochemical dual-aptamer-based sandwich detection of staphylococcus aureus.},
  author={Abdolkarim Abbaspour and Fatemeh Norouz-Sarvestani and Abolhassan Noori and Noushin Soltani},
  journal={Biosensors & bioelectronics},
  year={2015},
  volume={68},
  pages={149-155}
}
Staphylococcus aureus (S. aureus) is one of the most important human pathogens and causes numerous illnesses. In this study, we report a sensitive and highly selective dual-aptamer-based sandwich immunosensor for the detection of S. aureus. In this bioassay system, a biotinylated primary anti-S.aureus aptamer was immobilized on streptavidin coated magnetic beads (MB), which serves as a capture probe. A secondary anti-S.aureus aptamer was conjugated to silver nanoparticles (Apt-AgNP) that… CONTINUE READING
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