Aptamer conjugated paclitaxel and magnetic fluid loaded fluorescently tagged PLGA nanoparticles for targeted cancer therapy

  title={Aptamer conjugated paclitaxel and magnetic fluid loaded fluorescently tagged PLGA nanoparticles for targeted cancer therapy},
  author={A. Aravind and Remya Nair and S. Raveendran and S. Veeranarayanan and Y. Nagaoka and T. Fukuda and Takahashi Hasumura and H. Morimoto and Yasuhiko Yoshida and T. Maekawa and D. S. Kumar},
  journal={Journal of Magnetism and Magnetic Materials},
  • A. Aravind, Remya Nair, +8 authors D. S. Kumar
  • Published 2013
  • Chemistry
  • Journal of Magnetism and Magnetic Materials
  • Abstract Controlled and targeted drug delivery is an essential criterion in cancer therapy to reduce the side effects caused by non-specific drug release and toxicity. Targeted chemotherapy, sustained drug release and optical imaging have been achieved using a multifunctional nanocarrier constructed from poly (D, l -lactide-co-glycolide) nanoparticles (PLGA NPs), an anticancer drug paclitaxel (PTX), a fluorescent dye Nile red (NR), magnetic fluid (MF) and aptamers (Apt, AS1411, anti-nucleolin… CONTINUE READING
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