Aptamer-based electrochemical biosensor for detection of adenosine triphosphate using a nanoporous gold platform.

@article{KashefiKheyrabadi2013AptamerbasedEB,
  title={Aptamer-based electrochemical biosensor for detection of adenosine triphosphate using a nanoporous gold platform.},
  author={Leila Kashefi-Kheyrabadi and Masoud Ayatollahi Mehrgardi},
  journal={Bioelectrochemistry},
  year={2013},
  volume={94},
  pages={47-52}
}
In spite of the promising applications of aptamers in the bioassays, the development of aptamer-based electrochemical biosensors with the improved limit of detection has remained a great challenge. A strategy for the amplification of signal, based on application of nanostructures as platforms for the construction of an electrochemical adenosine triphosphate (ATP) aptasensor, is introduced in the present manuscript. A sandwich assay is designed by immobilizing a fragment of aptamer on a… CONTINUE READING
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