Aptamer/graphene oxide nanocomplex for in situ molecular probing in living cells.

@article{Wang2010AptamergrapheneON,
  title={Aptamer/graphene oxide nanocomplex for in situ molecular probing in living cells.},
  author={Ying Wang and Zhao-hui Li and Dehong Hu and Chiann-Tso Lin and Jinghong Li and Yuehe Lin},
  journal={Journal of the American Chemical Society},
  year={2010},
  volume={132 27},
  pages={9274-6}
}
Graphene has shown fascinating applications in bionanotechnology, including DNA sensing, protein assays, and drug delivery. However, exploration of graphene with intracellular monitoring and in situ molecular probing is still at an early stage. In this regard, we have designed an aptamer-carboxyfluorescein (FAM)/graphene oxide nanosheet (GO-nS) nanocomplex to investigate its ability for molecular probing in living cells. Results demonstrate that uptake of aptamer-FAM/GO-nS nanocomplex and… CONTINUE READING