Aprindine-induced hepatic granulomata.

@article{Elisaf1992AprindineinducedHG,
  title={Aprindine-induced hepatic granulomata.},
  author={Moses S Elisaf and Stella Stefanaki-Nikou and Michalis Voulgarelis and Constantine N. Masalas and Epameinondas Tsianos},
  journal={Journal of hepatology},
  year={1992},
  volume={14 2-3},
  pages={276-9}
}
Aprindine is a very effective antiarrhythmic agent with a narrow therapeutic ratio. We report a patient who suffered from granulomatous hepatitis probably due to the administration of aprindine. Evidence of hepatitis appeared within 6 weeks of initiating aprindine therapy and resolved rapidly when the drug was withdrawn. Six months later, fibrosis but no… CONTINUE READING