Appropriate use of fluoroquinolones in children.

  title={Appropriate use of fluoroquinolones in children.},
  author={Nicola Principi and Susanna Esposito},
  journal={International journal of antimicrobial agents},
  volume={45 4},
With the increasing resistance to antibiotics among common bacterial pathogens, challenges associated with the use of fluoroquinolones (FQs) in paediatrics have emerged. The majority of FQs have favourable pharmacokinetic properties, although these properties can differ in children compared with adults. Moreover, all FQs have broad antimicrobial activity both against Gram-positive and Gram-negative bacteria. However, only some FQs for which adequate studies are available have been approved for… CONTINUE READING
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