Approaches to improve the stability of the antiviral agent UC781 in aqueous solutions.


In this work, we evaluated the chemical stability profiles of UC781 based solutions to identify excipients that stabilize the microbicidal agent UC781. When different antioxidants were added to UC781 in sulfobutylether-beta-cyclodextrin (SBE-beta-CD) solutions and subjected to a 50 degrees C stability study, it was observed that EDTA was a better… (More)
DOI: 10.1016/j.ijpharm.2010.05.024


5 Figures and Tables