Approaches to determining regulatory values for carcinogens with particular reference to bromate.

Abstract

There are challenges in developing standards for substances that are carcinogenic in laboratory animals. In general, acceptable levels of substances that are shown to act through a mechanism that involves direct genotoxicity are determined by applying a mathematical model to extrapolate the risk at high doses to the risk at low environmental exposures. Most… (More)

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@article{Fawell2006ApproachesTD, title={Approaches to determining regulatory values for carcinogens with particular reference to bromate.}, author={John K Fawell and Mike Walker}, journal={Toxicology}, year={2006}, volume={221 2-3}, pages={149-53} }