Approaches to closed-loop deep brain stimulation for movement disorders.

  title={Approaches to closed-loop deep brain stimulation for movement disorders.},
  author={Chao-Hung Kuo and Gabrielle White-Dzuro and Andrew L. Ko},
  journal={Neurosurgical focus},
  volume={45 2},
OBJECTIVE Deep brain stimulation (DBS) is a safe and effective therapy for movement disorders, such as Parkinson's disease (PD), essential tremor (ET), and dystonia. There is considerable interest in developing "closed-loop" DBS devices capable of modulating stimulation in response to sensor feedback. In this paper, the authors review related literature and present selected approaches to signal sources and approaches to feedback being considered for deployment in closed-loop systems. METHODS A… 

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