Approaches to Salivary Cortisol Collection and Analysis in Infants
@article{Tryphonopoulos2014ApproachesTS,
title={Approaches to Salivary Cortisol Collection and Analysis in Infants},
author={Panagiota D Tryphonopoulos and Nicole L. Letourneau and Rima Azar},
journal={Biological Research For Nursing},
year={2014},
volume={16},
pages={398 - 408}
}Salivary cortisol is becoming more commonly utilized as a biologic marker of stress in observational studies and intervention research. However, its use with infants (12 months of age or younger) is less widespread and poses some special challenges to researchers. In order to decide on the most suitable collection procedure for salivary cortisol in infants, a number of criteria should be considered. This article will aid investigators interested in integrating salivary cortisol measurement into…
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References
SHOWING 1-10 OF 98 REFERENCES
Strategies for salivary cortisol collection and analysis in research with children.
- PsychologyApplied nursing research : ANR
- 2006
Measurement and meaning of salivary cortisol: A focus on health and disease in children
- MedicineStress
- 2008
The effects of gender, age, time and location of sampling, units of measurement, assay conditions and compliance with the protocol, all of which have the potential to impact upon the precision, accuracy and reliability of salivary cortisol measurements in the literature are addressed.
Salivary Cortisol As Indicators of Pain in Preterm Infants
- MedicineClinical nursing research
- 2004
Assessment and management of pain in preterm infants is critical and complicated. The addition of salivary cortisol measurement may improve the specificity of assessment and guide care to alleviate…
Salivary cortisol in preterm infants: Validation of a simple method for collecting saliva for cortisol determination.
- MedicineEarly human development
- 2007
Salivary cortisol measurements in sick infants: a feasible and objective method of measuring stress?
- Medicine
- 2005
Measuring salivary cortisol in studies of child development: watch out--what goes in may not come out of saliva collection devices.
- MedicineDevelopmental psychobiology
- 2007
Results reveal that for certain collection devices the percent volume recovered is related to the initial volume available to be absorbed, a substantial percentage of cortisol in saliva specimens can remain in absorbent material, and the percent of cortisol recovered can be associated with the initial sample volume available in absorbed.
Use of salivary cortisol measurements in young infants: a note of caution.
- MedicineChild development
- 1989
The present study suggests that appropriate controls should be taken when making salivary cortisol measurements in young infants to help ensure accurate results.
A re-investigation of saliva collection procedures that highlights the risk of potential positive interference in cortisol immunoassay
- Medicine, BiologySteroids
- 2009
Assessing salivary cortisol in studies of child development.
- Psychology, MedicineChild development
- 1998
Analysis of samples collected using oral stimulants from child and adult participants confirmed stimulant interference as an extraneous source of variability in measured saliva cortisol, and recommendations to minimize the impact of stimulant interfered in studies involving salivary cortisol in the context of child health and development are outlined.
Circadian rhythm of salivary cortisol, 17alpha-hydroxyprogesterone, and progesterone in healthy children.
- Medicine, BiologyClinical chemistry
- 2003
Age-dependent reference values for salivary cortisol, 17α-hydroxyprogesterone (17OHP), and progesterone in a large cohort of healthy children are established to improve the applicability of saliva analysis as a diagnostic tool in pediatric endocrinology.