Approaches for establishing predicted-no-effect concentrations for population-level ecological risk assessment in the context of chemical substances management.

@article{Lin2005ApproachesFE,
  title={Approaches for establishing predicted-no-effect concentrations for population-level ecological risk assessment in the context of chemical substances management.},
  author={Bin-Le Lin and Akihiro Tokai and Junko Nakanishi},
  journal={Environmental science & technology},
  year={2005},
  volume={39 13},
  pages={4833-40}
}
The establishment of rational frameworks for population-level ecological risk assessment (PLERA) in the context of chemical substances management is an important issue. We illustrate two feasible approaches for establishing predicted-no-effect concentrations (PNECs)for PLERA through a case study of 4-nonylphenol (4-NP) using life-cycle toxicity data for medaka (Oryzias latipes). We first quantified the potential impacts of 4-NP on medaka in terms of reduction of population growth rate (i). An… CONTINUE READING

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