Applying small molecule microarrays and resulting affinity probe cocktails for proteome profiling of mammalian cell lysates.

Abstract

Small molecule microarrays (SMMs) are proving to be increasingly important tools for assessing protein-ligand interactions, as well as in screening for enzyme substrates and inhibitors, in a high-throughput manner. We previously described an SMM-facilitated screening strategy for the rapid identification of probes against γ-secretase, an aspartic protease… (More)
DOI: 10.1002/asia.201100523

Topics

Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.

Slides referencing similar topics