Applying small molecule microarrays and resulting affinity probe cocktails for proteome profiling of mammalian cell lysates.


Small molecule microarrays (SMMs) are proving to be increasingly important tools for assessing protein-ligand interactions, as well as in screening for enzyme substrates and inhibitors, in a high-throughput manner. We previously described an SMM-facilitated screening strategy for the rapid identification of probes against γ-secretase, an aspartic protease… (More)
DOI: 10.1002/asia.201100523


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