Applied molecular biology of sepsis.

  title={Applied molecular biology of sepsis.},
  author={Daniel G Remick},
  journal={Journal of critical care},
  volume={10 4},
The effective treatment of sepsis and septic shock has remained elusive despite intense research efforts. The tools of molecular biology have been applied to the problem of sepsis in an attempt to design more rational, directed therapy. Cellular interactions with invading microorganisms begin a series of stimulation events within the cell. One of the important interactions is the binding of lipopolysaccharide (LPS) from gram-negative bacteria to the LPS binding protein, and then this complex… CONTINUE READING


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