Applications of transfected cell microarrays in high-throughput drug discovery.

@article{Bailey2002ApplicationsOT,
  title={Applications of transfected cell microarrays in high-throughput drug discovery.},
  author={Steve N Bailey and Randy Z. Wu and David M. Sabatini},
  journal={Drug discovery today},
  year={2002},
  volume={7 18 Suppl},
  pages={S113-8}
}
DNA microarrays and, more recently, protein microarrays, have become important tools for high-throughput genomic and proteomic studies. Transfected cell microarrays are a complementary technique in which array features comprise clusters of cells overexpressing defined cDNAs. Complementary DNAs cloned in expression vectors are printed on microscope slides, which become living arrays after the addition of a lipid transfection reagent and adherent mammalian cells. This article discusses two… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 17 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 28 references

Global analysis of protein activities using proteome

  • H Zhu
  • chips. Science
  • 2001

Global analysis of protein activities using proteome chips

  • J. Ziauddin, D. M. Sabatini
  • Science
  • 2001

Mechanism of action of trastuzumab and scientific update

  • J Baselga
  • Semin. Oncol
  • 2001

RNA interference

  • P. A. Sharp
  • Genes Dev
  • 2001

Similar Papers

Loading similar papers…