Applications of respiratory mass spectrometry to intensive care
@article{Gothard1980ApplicationsOR, title={Applications of respiratory mass spectrometry to intensive care}, author={John W.W. Gothard and C M Busst and Margaret A. Branthwaite and N. J. H. Davies and David M. Denison}, journal={Anaesthesia}, year={1980}, volume={35} }
A monitoring and research system based on a respiratory mass spectrometer controlled by a microprocessor has been installed in a paediatric intensive care unit. It provides an opportunity to study up to twelve patients simultaneously at distances up to 30 m from the instrument, can operate for prolonged periods without intervention, and includes a routine for regular calibration checks. There is an automatic sensitivity control which compensates for minor variations in probe patency or in water…
25 Citations
Respiratory mass spectrometry during general anaesthesia.
- Environmental ScienceBritish journal of anaesthesia
- 1981
The performance of a respiratory mass spectrometer, modified commercially for use during general anaesthesia, has been evaluated. Stability and linearity proved satisfactory for monitoring…
Mass Spectrometry in the Intensive Care Unit
- Medicine
- 1981
This report evaluates a system, based on the Centronic MGA 200 respiratory mass spectrometer, which has been installed in the intensive care unit of a specialised cardiothoracic hospital.
Remote monitoring by mass spectrometry during anaesthesia. Evaluation of a suitable inlet system.
- EngineeringBritish journal of anaesthesia
- 1982
Results compared with those of other workers support the chosen compromise between practical flexibility and convenience versus maximum speed of response that was adopted in this system design.
An automated mechanism for protection of mass spectrometry sampling tubing
- EngineeringJournal of Clinical Monitoring
- 2005
An automated system consisting of an infrared light sensor and a three-way valve that has decreased the cost of operating mass spectrometers while also reducing periods of unavailability due to equipment failure is developed.
A multipatient mass spectrometer based system for the measurement of metabolic gas exchange in artificially ventilated intensive care patients
- MedicineIntensive Care Medicine
- 2005
The MPMS measurements of metabolic gas exchange were found to have insignificant systematic errors with precisions of ±12 ml/min VO2, ±7 ml/Min VCO2,±0.03 RQ and ±0.1 l/min Ve; (2SD).
Evaluation of long sampling tubes for remote monitoring by mass spectrometry
- Environmental ScienceJournal of Clinical Monitoring
- 2008
The long sampling tubes required for remote mass spectrometry alter the sampling system’s performance characterized by sample flow, residence time, and 10 to 90% response time, so an easy-to-handle tube is searched for that allows the accurate monitoring of breathing frequencies up to 25 and 50 breaths/min for volatile agents and gases.
Monitoring respiratory function in the critically ill
- Environmental ScienceIntensive Care Medicine
- 2005
Equipment has been developed which allows breath by breath recording of carbon dioxide concentration using stable, simple apparatus which does not require frequent recalibration with known gas mixtures and is suitable for use in both spontaneously breathing, conscious subjects and for those requiring mechanical ventilation.
A gas mixer for computer calibration of an anesthetic mass spectrometer
- Environmental ScienceJournal of Clinical Monitoring
- 2008
To calibrate an anesthetic mass spectrometer without the use of premixed gases and vapors in cylinders, we devised a gas mixer using fixed resistances of capillary needle tubings and adjustable…
End-tidal carbon dioxide as a measure of arterial carbon dioxide during intermittent mandatory ventilation
- MedicineJournal of Clinical Monitoring
- 2004
Monitoring the maximalPetCO2, independent of breathing pattern, provides a clinically useful indicator of PaCO2 in postcardiotomy patients receiving intermittent mandatory ventilation.
References
SHOWING 1-10 OF 11 REFERENCES
The uses of long sampling probes in respiratory mass spectrometry.
- ChemistryRespiration physiology
- 1979
The measurement of metabolic gas exchange and minute volume by mass spectrometry alone.
- MedicineRespiration physiology
- 1979
A pressure-operated collect valve for respiratory studies during intermittent positive pressure ventilation.
- MedicineBritish journal of anaesthesia
- 1969
During the inflation phase of intermittent positive pressure ventilation gas is compressed in the tubes and connections between the valves of the ventilator and the patient. In machines where the…
BEDSIDE REBREATHING TECHNIQUE FOR MEASURING CARBON-MONOXIDE UPTAKE BY THE LUNG
- MedicineThe Lancet
- 1978
A system for monitoring arterial oxygen tension in sick newborn babies.
- MedicineBiomedical engineering
- 1975
The results obtained with these transducers in the first eighteen babies are reported in detail and demonstrate the possibility of continuous, reliable measurement of PaO2 under routine clinical conditions.
Lung tissue volume and blood flow by rebreathing theory.
- MedicineJournal of applied physiology: respiratory, environmental and exercise physiology
- 1978
Estimates of Vt and Qc have acceptable accuracy in normal man and subjects with moderate degree of uneven distribution, but large errors develop with more severe forms of lung disease.
Electronic compensation of the effects of water vapor in respiratory mass spectrometry.
- Chemistry, MedicineJournal of applied physiology
- 1971
pressure-operated collected valve for respiratory studies during intermittent positive pressure ventilation
- British Journal of Anaesthesia
- 1969
The use of long sampling probes in respiratory mass spectrometry. Respiration
- Physiology
- 1979