Applications of peptide nucleic acids (PNAs) and locked nucleic acids (LNAs) in biosensor development.

Abstract

Nucleic acid biosensors have a growing number of applications in genetics and biomedicine. This contribution is a critical review of the current state of the art concerning the use of nucleic acid analogues, in particular peptide nucleic acids (PNA) and locked nucleic acids (LNA), for the development of high-performance affinity biosensors. Both PNA and LNA… (More)
DOI: 10.1007/s00216-012-5742-z

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