Applications of new sequencing technologies for transcriptome analysis.

@article{Morozova2009ApplicationsON,
  title={Applications of new sequencing technologies for transcriptome analysis.},
  author={O. L. Morozova and Martin Hirst and Marco A. Marra},
  journal={Annual review of genomics and human genetics},
  year={2009},
  volume={10},
  pages={135-51}
}
Transcriptome analysis has been a key area of biological inquiry for decades. Over the years, research in the field has progressed from candidate gene-based detection of RNAs using Northern blotting to high-throughput expression profiling driven by the advent of microarrays. Next-generation sequencing technologies have revolutionized transcriptomics by providing opportunities for multidimensional examinations of cellular transcriptomes in which high-throughput expression data are obtained at a… CONTINUE READING

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