Applications of imaging techniques to studies of epithelial tight junctions.

@article{Johnson2005ApplicationsOI,
  title={Applications of imaging techniques to studies of epithelial tight junctions.},
  author={Larry G. Johnson},
  journal={Advanced drug delivery reviews},
  year={2005},
  volume={57 1},
  pages={111-21}
}
The intercellular junctional complex, which consists of the tight junction (TJ), adherens junction, and desmosomes, mediates cell-cell adhesion in epithelia and endothelia. The TJ forms the apical-most portion of this complex in epithelia, serving as a fence to lateral diffusion of apical and basolateral membrane components and as a semi-permeable barrier or gate to the flow of ions and solutes through the paracellular pathway. The TJ consists of a series of integral membrane and cytoplasmic… CONTINUE READING

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