Applications of imaging techniques to studies of epithelial tight junctions.

  title={Applications of imaging techniques to studies of epithelial tight junctions.},
  author={Larry G. Johnson},
  journal={Advanced drug delivery reviews},
  volume={57 1},
The intercellular junctional complex, which consists of the tight junction (TJ), adherens junction, and desmosomes, mediates cell-cell adhesion in epithelia and endothelia. The TJ forms the apical-most portion of this complex in epithelia, serving as a fence to lateral diffusion of apical and basolateral membrane components and as a semi-permeable barrier or gate to the flow of ions and solutes through the paracellular pathway. The TJ consists of a series of integral membrane and cytoplasmic… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.


Publications citing this paper.
Showing 1-9 of 9 extracted citations


Publications referenced by this paper.
Showing 1-10 of 91 references

The coxsackievirus and adenovirus receptor is a transmembrane component of the tight junction.

Proceedings of the National Academy of Sciences of the United States of America • 2001
View 6 Excerpts
Highly Influenced

Occludin: a novel integral membrane protein localizing at tight junctions

The Journal of cell biology • 1993
View 6 Excerpts
Highly Influenced

Balda , Holey barrier : claudins and the regulation of brain endothelial permeability

M. S. K. Matter
J . Cell Sci . • 2004

The role of claudins in determining paracellular charge selectivity

C. Van Itallie, J. M. Anderson
Proc. Am. Thorac. Soc. 1 • 2004
View 1 Excerpt

Similar Papers

Loading similar papers…