Applications of hydrophilic interaction chromatography to amino acids, peptides, and proteins.

@article{Priat2015ApplicationsOH,
  title={Applications of hydrophilic interaction chromatography to amino acids, peptides, and proteins.},
  author={Aur{\'e}lie P{\'e}riat and Ira S. Krull and Davy Guillarme},
  journal={Journal of separation science},
  year={2015},
  volume={38 3},
  pages={
          357-67
        }
}
This review summarizes the recent advances in the analysis of amino acids, peptides, and proteins using hydrophilic interaction chromatography. Various reports demonstrate the successful analysis of amino acids under such conditions. However, a baseline resolution of the 20 natural amino acids has not yet been published and for this reason, there is often a need to use mass spectrometry for detection to further improve selectivity. Hydrophilic interaction chromatography is also recognized as a… CONTINUE READING
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