Applications of computational algorithm tools to identify functional SNPs in cytokine genes.

@article{Shen2006ApplicationsOC,
  title={Applications of computational algorithm tools to identify functional SNPs in cytokine genes.},
  author={Jie Shen and Prescott L Deininger and Hua Zhao},
  journal={Cytokine},
  year={2006},
  volume={35 1-2},
  pages={62-6}
}
Understanding the functions of single nucleotide polymorphisms (SNPs) can greatly help to understand the genetics of the human phenotype variation and especially the genetic basis of human complex diseases. However, how to identify functional SNPs from a pool containing both functional and neutral SNPs is challenging. In this study, we analyzed the genetic variations that can alter the expression and function of a group of cytokine proteins using computational tools. As a result, we extracted… CONTINUE READING

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