Applications of circular dichroism in protein and peptide analysis

  title={Applications of circular dichroism in protein and peptide analysis},
  author={N. Greenfield},
  journal={Trends in Analytical Chemistry},
  • N. Greenfield
  • Published 1999
  • Chemistry
  • Trends in Analytical Chemistry
  • Abstract This review discusses several useful applications of circular dichroism as a tool for analyzing properties of proteins. The following topics are discussed: (1) protein–ligand interactions; (2) thermodynamics of protein folding; (3) conformational transitions and protein aggregation; (4) folding intermediates; (5) kinetics of protein folding. Specific examples are given to illustrate each application. 
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