Applications of cellular systems biology in breast cancer patient stratification and diagnostics.

@article{CritchleyThorne2009ApplicationsOC,
  title={Applications of cellular systems biology in breast cancer patient stratification and diagnostics.},
  author={Rebecca J. Critchley-Thorne and Steven M. Miller and D. Lansing Taylor and Wilma L. Lingle},
  journal={Combinatorial chemistry & high throughput screening},
  year={2009},
  volume={12 9},
  pages={
          860-9
        }
}
Tumors are complex structures of malignant cells and stromal cells that function as an integrated system that promotes tumor progression. Immune cells and other stromal components serve vital cooperative functions that often support tumor growth and metastasis; stromal content and function are strongly associated with disease progression and clinical outcome in cancer patients. Cellular systems biology considers tissues and tumors, and the cells within them, as integrated and interactive… CONTINUE READING

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