Applications of aptamers as sensors.

@article{Cho2009ApplicationsOA,
  title={Applications of aptamers as sensors.},
  author={Eun Jeong Cho and Joo-Woon Lee and Andrew D. Ellington},
  journal={Annual review of analytical chemistry},
  year={2009},
  volume={2},
  pages={
          241-64
        }
}
Aptamers are ligand-binding nucleic acids whose affinities and selectivities can rival those of antibodies. They have been adapted to analytical applications not only as alternatives to antibodies, but as unique reagents in their own right. In particular, aptamers can be readily site-specifically modified during chemical or enzymatic synthesis to incorporate particular reporters, linkers, or other moieties. Also, aptamer secondary structures can be engineered to undergo analyte-dependent… CONTINUE READING

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