Applications of a mouse model of calvarial healing: differences in regenerative abilities of juveniles and adults.

Abstract

Young children are capable of healing large calvarial defects, whereas adults lack this endogenous osseous tissue-engineering capacity. Despite the important clinical implications, little is known about the molecular and cell biology underlying this differential ability. Traditionally, guinea pig, rabbit, and rat models have been used to study the… (More)

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@article{Aalami2004ApplicationsOA, title={Applications of a mouse model of calvarial healing: differences in regenerative abilities of juveniles and adults.}, author={Oliver O. Aalami and Randall P Nacamuli and Kelly A Lenton and Catherine M. Cowan and Tony D Fang and Kenton D Fong and Yun-Ying Shi and Hanjoon M Song and David E. Sahar and Michael Thornton Longaker}, journal={Plastic and reconstructive surgery}, year={2004}, volume={114 3}, pages={713-20} }