Application of the NT solvent nucleophilicity scale to attack at phosphorus: solvolyses of N,N,N',N'-tetramethyldiamidophosphorochloridate.

@article{Kevill2002ApplicationOT,
  title={Application of the NT solvent nucleophilicity scale to attack at phosphorus: solvolyses of N,N,N',N'-tetramethyldiamidophosphorochloridate.},
  author={Dennis Neil Kevill and Bronwyn Miller},
  journal={The Journal of organic chemistry},
  year={2002},
  volume={67 21},
  pages={7399-406}
}
The specific rates of solvolysis of N,N,N',N'-tetramethyldiamidophosphorochloridate have been measured at 25.0 degrees C in 31 solvents. Analysis with the extended Grunwald-Winstein equation leads to sensitivities toward changes in solvent nucleophilicity (l) of 1.20 +/- 0.07 and toward changes in solvent ionizing power (m) of 0.69 +/- 0.04. The correlation is improved by omission of the four data points for 2,2,2-trifluoroethanol-ethanol mixtures (F-test value from 155 to 320) with very small… CONTINUE READING