Application of six hepatitis C virus genotyping systems to sera from chronic hepatitis C patients in the United States.

@article{Lau1995ApplicationOS,
  title={Application of six hepatitis C virus genotyping systems to sera from chronic hepatitis C patients in the United States.},
  author={Johnson Y. N. Lau and Masashi Mizokami and Janice A. Kolberg and Gary L. Davis and L E Prescott and Tomoyoshi Ohno and Robert P. Perrillo and Karen L Lindsay and Robert Gish and Keda Qian},
  journal={The Journal of infectious diseases},
  year={1995},
  volume={171 2},
  pages={281-9}
}
Serum samples from 139 US patients with chronic hepatitis C virus (HCV) infection were studied using six different genotyping systems, including both molecular and serologic methods, to determine the applicability of these approaches and the prevalence of various HCV subtypes. The concordance of genotyping results based on the various systems (except for core polymerase chain reaction genotyping) was good (93.5%). Subtypes 1a and 1b were prevalent (37.4%). Subtypes 2a (2.2%), 2b (8.6%), and 3a… CONTINUE READING