Application of single-cell cultures of mouse splenocytes as an assay system to analyze the immunomodulatory properties of bacterial components.

Abstract

Recently, various bacterial components have been suggested as initiating and modulating immune activation, thereby substantially affecting the complex and dynamic host/pathogen interactions. Herein, we present a valuable and simple methodology for determining the capacity of bacteria as well as defined bacterial structures to stimulate cellular effectors of… (More)

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