Application of selected reaction monitoring and parallel reaction monitoring for investigation of HL-60 cell line differentiation

@article{Novikova2017ApplicationOS,
  title={Application of selected reaction monitoring and parallel reaction monitoring for investigation of HL-60 cell line differentiation},
  author={S. Novikova and O. Tikhonova and L. Kurbatov and T. Farafonova and I. Vakhrushev and V. Zgoda},
  journal={European Journal of Mass Spectrometry},
  year={2017},
  volume={23},
  pages={202 - 208}
}
  • S. Novikova, O. Tikhonova, +3 authors V. Zgoda
  • Published 2017
  • Medicine, Chemistry
  • European Journal of Mass Spectrometry
  • Targeted mass spectrometry represents a powerful tool for investigation of biological processes. The convenient approach of selected reaction monitoring using stable isotope-labeled peptide standard (SIS) is widely applied for protein quantification. Along with this method, high-resolution parallel reaction monitoring has been increasingly used for protein targeted analysis. Here we applied two targeted approaches (selected reaction monitoring with SIS and label-free parallel reaction… CONTINUE READING
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