Application of second harmonic imaging microscopy to assess structural changes in optic nerve head structure ex vivo.

@article{Brown2007ApplicationOS,
  title={Application of second harmonic imaging microscopy to assess structural changes in optic nerve head structure ex vivo.},
  author={D. Brown and N. Morishige and A. Neekhra and D. Minckler and J. Jester},
  journal={Journal of biomedical optics},
  year={2007},
  volume={12 2},
  pages={
          024029
        }
}
  • D. Brown, N. Morishige, +2 authors J. Jester
  • Published 2007
  • Materials Science, Medicine
  • Journal of biomedical optics
  • Glaucoma represents the second leading cause of blindness worldwide. While both age and intraocular pressure (IOP) are well-recognized risk factors for this disease, the underlying pathologic process involves the accelerated death of retinal ganglion cells (RGCs) that is associated with progressive loss of vision. The loss of RGCs has been postulated to occur primarily by injury to axons in the optic nerve head (ONH) due to its anatomic features and the mechanical vulnerability of the lamina… CONTINUE READING
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