Application of rhBMP-7 and platelet-rich plasma in the treatment of long bone non-unions: a prospective randomised clinical study on 120 patients.

@article{Calori2008ApplicationOR,
  title={Application of rhBMP-7 and platelet-rich plasma in the treatment of long bone non-unions: a prospective randomised clinical study on 120 patients.},
  author={Giorgio Maria Calori and Lorenzo Tagliabue and Luca Gala and Marco d'Imporzano and Giovanni Peretti and Walter Albisetti},
  journal={Injury},
  year={2008},
  volume={39 12},
  pages={1391-402}
}
The purpose of this prospective randomised clinical study was to compare the efficacy of recombinant bone morphogenetic protein 7 (rhBMP-7) and platelet-rich plasma (PRP) as bone-stimulating agents in the treatment of persistent fracture non-unions. One hundred and twenty patients were randomised into two treatment groups (group rhBMP-7 vs. group PRP). Sixty patients with sixty fracture non-unions were assigned to each group (median age: 44 years, range 19-65, for the rhBMP-7 group and 41 years… CONTINUE READING
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