Application of real-time confocal microscopy to intracellular calcium ion dynamics in rat arterioles

@article{Saino2002ApplicationOR,
  title={Application of real-time confocal microscopy to intracellular calcium ion dynamics in rat arterioles},
  author={Tomoyuki Saino and Makoto Matsuura and Yoh-ichi Satoh},
  journal={Histochemistry and Cell Biology},
  year={2002},
  volume={117},
  pages={295-305}
}
The regulation of cytosolic Ca2+ homeostasis is essential for cells, including vascular smooth muscle cells. Arterial tone, which underlies the maintenance of peripheral resistance in the circulation, is a major contributor to the control of blood pressure. Confocal microscopy was employed to study the alteration in intracellular calcium ion concentration ([Ca2+]i) in arterioles (external diameters <100 µm) with respect to selected modifying reagents. 5-Hydroxytryptamine (1 µM), ATP (10 µM… CONTINUE READING
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