Application of quantitative structure activity relationship (QSAR) models to predict ozone toxicity in the lung.

Abstract

The sequence of events leading to ozone-induced airway inflammation is not well known. To elucidate the molecular and cellular events underlying ozone toxicity in the lung, we hypothesized that lipid ozonation products (LOPs) generated by the reaction of ozone with unsaturated fatty acids in the epithelial lining fluid and cell membranes play a key role in… (More)

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@article{Kafoury2005ApplicationOQ, title={Application of quantitative structure activity relationship (QSAR) models to predict ozone toxicity in the lung.}, author={Ramzi M. Kafoury and Ming-Ju Huang}, journal={Environmental toxicology}, year={2005}, volume={20 4}, pages={441-8} }