Application of proteomic profiling based on 2D-DIGE for classification of compounds according to the mechanism of action.

Abstract

The development of new anticancer agents derived from natural resources requires a rapid identification of their molecular mechanism of action. To make this step short, we have initiated the proteomic profiling of HeLa cells treated with anticancer drugs representing a wide spectrum of mechanisms of action using two-dimensional difference gel… (More)
DOI: 10.1016/j.chembiol.2010.03.016

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Cite this paper

@article{Muroi2010ApplicationOP, title={Application of proteomic profiling based on 2D-DIGE for classification of compounds according to the mechanism of action.}, author={Makoto Muroi and Sayaka Kazami and Kazue Noda and Hisae Kondo and Hiroshi Takayama and M. Kawatani and Takeo Usui and Hiroyuki Osada}, journal={Chemistry & biology}, year={2010}, volume={17 5}, pages={460-70} }