Application of pooled genotyping to scan candidate regions for association with HDL cholesterol levels

Abstract

Association studies are used to identify genetic determinants of complex human traits of medical interest. With the large number of validated single nucleotide polymorphisms (SNPs) currently available, two limiting factors in association studies are genotyping capability and costs. Pooled DNA genotyping has been proposed as an efficient means of screening… (More)
DOI: 10.1186/1479-7364-1-6-421

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