Application of nanosheets as an anti-adhesion barrier in partial hepatectomy.

  title={Application of nanosheets as an anti-adhesion barrier in partial hepatectomy.},
  author={Daisuke Niwa and Masatsugu Koide and Toshinori Fujie and Nobuhito Goda and Shinji Takeoka},
  journal={Journal of biomedical materials research. Part B, Applied biomaterials},
  volume={101 7},
Postoperative adhesion often causes serious adverse effects such as bowl obstruction, chronic abdominal pain, pelvic pain, and infertility. We previously reported that a poly-L-lactic acid (PLLA) nanosheet can efficiently seal a surgical incision without scarring. In this report, we examined whether the PLLA nanosheet can form an effective anti-adhesion barrier in partial hepatectomy accompanied by severe hemorrhaging in rats. To evaluate the anti-adhesive property of the nanosheet, the liver… CONTINUE READING