Application of nano-LC-MALDI-TOF/TOF-MS for proteomic analysis of microvesicles.

@article{Kasprzyk2017ApplicationON,
  title={Application of nano-LC-MALDI-TOF/TOF-MS for proteomic analysis of microvesicles.},
  author={Joanna Kasprzyk and Ewa Ł Stępień and Wojciech Piekoszewski},
  journal={Clinical biochemistry},
  year={2017},
  volume={50 4-5},
  pages={241-243}
}
Activated platelets and platelet derived microvesicles (PMVs) emerged recently to be promising biomarkers. There is no universal procedure to carry out the proteomic analysis on microvesicles. In this study we proposed a nano-liquid chromatography (nano-LC) technique coupled off-line with a spectrometric measurement MALDI-TOF-MS/MS as a throughput and time… CONTINUE READING